Dong Qiang

  • Le chant d'amour à la poésie par un grand écrivain contemporain

    Je suis entré dans la poésie Tang presque à l'improviste, mais non par hasard, en lisant un poème de Li Bai, qui met face à face un homme et une montagne. Le poète décrit un lieu d'immobilité et de majesté devant lequel l'être humain, dans sa faiblesse et son impermanence, ne peut que s'asseoir et regarder.

    Li Bai m'apportait autre chose, à quoi je n'étais pas préparé par mon éducation et par mon langage : une plénitude, une paix intérieure. Cette paix n'était pas difficile à atteindre. Il suffisait de s'asseoir et de regarder.

    La poésie Tang est sans doute le moyen de garder ce contact avec le monde réel, elle nous invite au voyage hors de nous-mêmes, nous fait partager les règnes, les durées, les rêves.

    J.M.G. Le Clézio

  • Multiscale Simulations and Mechanics of Biological Materials  A compilation of recent developments in multiscale simulation and computational biomaterials written by leading specialists in the field Presenting the latest developments in multiscale mechanics and multiscale simulations, and offering a unique viewpoint on multiscale modelling of biological materials, this book outlines the latest developments in computational biological materials from atomistic and molecular scale simulation on DNA, proteins, and nano-particles, to meoscale soft matter modelling of cells, and to macroscale soft tissue and blood vessel, and bone simulations. Traditionally, computational biomaterials researchers come from biological chemistry and biomedical engineering, so this is probably the first edited book to present work from these talented computational mechanics researchers.  The book has been written to honor Professor Wing Liu of Northwestern University, USA, who has made pioneering contributions in multiscale simulation and computational biomaterial in specific simulation of drag delivery at atomistic and molecular scale and computational cardiovascular fluid mechanics via immersed finite element method. Key features: Offers a unique interdisciplinary approach to multiscale biomaterial modelling aimed at both accessible introductory and advanced levels Presents a breadth of computational approaches for modelling biological materials across multiple length scales (molecular to whole-tissue scale), including solid and fluid based approaches  A companion website for supplementary materials plus links to contributors' websites (www.wiley.com/go/li/multiscale)

  • An integrated view of chiral drugs-from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies-asymmetric synthesis, biocatalytic process, and chiral resolution-to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective-and safer-drugs.

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