In Vivo Models of Inflammation provides the biomedical researcher with a description of the state of the art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first edition by describing and updating the standard models that are most utilized for specific disease areas. In addition, new models are included exploring emerging areas of inflammation research.
New approaches to the development of future models in selected therapeutic areas have been highlighted. The focus on novel technologies that are vital for innovative in vivo research has also been expanded to include chapters on the use of transgenic and gene transfer technologies, nanotechnology, and stem cells.
The aim of this book is to provide current best practices for obtaining the maximum information from in vivo experimentation, while preserving the dignity and comfort of the animal.
This completely revised and corrected version of the well-known Florence notes circulated by the authors together with E. Friedlander examines basic topology, emphasizing homotopy theory. Included is a discussion of Postnikov towers and rational homotopy theory. This is then followed by an in-depth look at differential forms and de Tham's theorem on simplicial complexes. In addition, Sullivan's results on computing the rational homotopy type from forms is presented. New to the Second Edition: *Fully-revised appendices including an expanded discussion of the Hirsch lemma*Presentation of a natural proof of a Serre spectral sequence result *Updated content throughout the book, reflecting advances in the area of homotopy theoryWith its modern approach and timely revisions, this second edition of Rational Homotopy Theory and Differential Forms will be a valuable resource for graduate students and researchers in algebraic topology, differential forms, and homotopy theory.
