Philippe Grandjean

  • Une analyse détaillée de la pièce de Victor Hugo, au programme de littérature pour le bac 2019-2020  : sa genèse, sa réception et ses caractéristiques littéraires clés.
     
    Pour les deux sessions du bac 2019 et 2020, Hernani est au programme de littérature française en terminale L, dans le cadre du domaine d'étude «  Lire, écrire, publier ».
     
    Ce Profil du bac en propose une analyse approfondie. Il permet notamment de mieux comprendre comment cette pièce de théâtre a constitué un véritable événement littéraire en 1830 et est devenue emblématique du romantisme.
     

  • On a beaucoup écrit sur la deuxième Guerre mondiale et sur la guerre d'Indochine (1949-1954). Mais très peu sur l'étonnante aventure de l'Indochine dans la deuxième Guerre mondiale (1940-1945). Isolée, soudain, d'une métropole écrasée en juin 1940, l'Indochine française de l'amiral Decoux est restée, après 1942, le seul îlot "blanc" dans le raz de marée nippon d'après Pearl Harbor. Cet "incroyable pari", suivant le mot de L. Bodard, a tenu cinq ans. Pourquoi le 9 mars 1945, Tokyo a-t-il été conduit à balayer l'imperium français? Le 9 mars 1945 a engendré la guerre d'Indochine.

  • Aujourd'hui, un enfant sur six souffre d'une anomalie du développement neurologique, un sur huit de déficit de l'attention, un sur soixante-huit d'un trouble du spectre autistique. Ce livre est un cri d'alarme. Il montre comment des produits chimiques - le mercure, l'arsenic, le plomb, les pesticides, les PCB, etc. - que nous croisons tous les jours dans nos environnements, menacent, de façon insidieuse, le développement du cerveau. Cet empoisonnement invisible commence dès les premiers instants de la vie, alors que l'enfant se trouve encore dans le ventre de sa mère. Or, le cerveau, organe particulièrement vulnérable, est unique, irremplaçable. Les dégâts sont irréversibles et lourds de conséquences pour l'individu comme pour la société. Il est urgent de réagir ! Les solutions existent, mais elles nécessitent une prise de conscience immédiate. Certains poisons, déjà identifiés, doivent être interdits. Nous devons également exiger des tests systématiques pour tout nouvel élément mis sur le marché, ainsi que des contrôles de nos industries. Il est encore possible de protéger les générations futures et il ne faut plus attendre !

  • La performance est un concept qui a envahi le monde de la santé à tous les niveaux. Ce concept est cependant difficile à appréhender : la performance comporte de multiples dimensions dont chacune n´éclaire qu´un aspect de la question. En outre, il fait - entre autres - référence à la dimension économique du soin qui n´est pas spontanément ancrée dans le secteur. Une approche globale portant non seulement sur chacune des dimensions, mais également sur le produit de leurs interactions, est nécessaire pour rendre compte du concept. Un éclairage selon les points de vue des différentes parties prenantes du système de santé est également à considérer pour comprendre toute la complexité du déploiement et du pilotage de la performance au niveau macro et microéconomique. L´objet de cet ouvrage est d´éclairer d´un point de vue théorique mais également pratique, les différentes dimensions de la performance dans le champ de la santé.

  • Today, one out of every six children suffers from some form of neurodevelopmental abnormality. The causes are mostly unknown. Some environmental chemicals are known to cause brain damage and many more are suspected of it, but few have been tested for such effects. Philippe Grandjean provides an authoritative and engaging analysis of how environmental hazards can damage brain development and what we can do about it.
    The brain's development is uniquely sensitive to toxic chemicals, and even small deficits may negatively impact our academic achievements, economic success, risk of delinquency, and quality of life. Chemicals such as mercury, polychlorinated biphenyls (PCBs), arsenic, and certain pesticides pose an insidious threat to the development of the next generation's brains. When chemicals in the environment affect the development of a child's brain, he or she is at risk for mental retardation, cerebral palsy, autism, ADHD, and a range of learning disabilities and other deficits that will remain for a lifetime.
    We can halt chemical brain drain and protect the next generation, however, and Grandjean tells us how. First, we need to control all of the 200 industrial chemicals that have already been proven to affect brain functions in adults, as their effects on the developing brain are likely even worse. We must also push for routine testing for brain toxicity, stricter regulation of chemical emissions, and more required disclosure on the part of industries who unleash hazardous chemicals into products and the environment. Decisions can still be made to protect the brains of future generations.
    "In his crisply written, deeply documented book, Dr. Philippe Grandjean, renowned physician and public health specialist, describes the exquisite vulnerability of the developing human brain to toxic chemicals in the environment, a vulnerability that he ascribes to the brain's almost unimaginable complexity. Today, nearly one in every 6 children is born with a neurodevelopmental disorder - a birth defect of the brain. One in 8 has attention deficit disorder. One in 88 is diagnosed with autism spectrum disorder. These rates are far higher than those of a generation ago, and, although they are less publicized, the problems are more prevalent than those caused by thalidomide in the 1960's. The increases are far too rapid to be genetic. They cannot be explained by better diagnosis. How then could they have come to be? Dr. Grandjean has a diagnosis -- the thousands of toxic chemicals that have been released to the environment in the past 40 years with no testing for toxicity. David P. Rall, former Director of the US National Institute of Environmental Health Sciences, once stated that 'If thalidomide had caused a ten-point loss of IQ rather than obvious birth defects of the limbs, it would probably still be on the market'. This is the core message of Dr. Grandjean's 'must read' book." - Philip J. Landrigan, Dean for Global Health, Ethel H. Wise Professor and Chairman and Director, Children's Environmental Health Center, Mount Sinai School of Medicine

  • Today, one out of every six children suffers from some form of neurodevelopmental abnormality. The causes are mostly unknown. Some environmental chemicals are known to cause brain damage and many more are suspected of it, but few have been tested for such effects. Philippe Grandjean provides an authoritative and engaging analysis of how environmental hazards can damage brain development and what we can do about it.
    The brain's development is uniquely sensitive to toxic chemicals, and even small deficits may negatively impact our academic achievements, economic success, risk of delinquency, and quality of life. Chemicals such as mercury, polychlorinated biphenyls (PCBs), arsenic, and certain pesticides pose an insidious threat to the development of the next generation's brains. When chemicals in the environment affect the development of a child's brain, he or she is at risk for mental retardation, cerebral palsy, autism, ADHD, and a range of learning disabilities and other deficits that will remain for a lifetime.
    We can halt chemical brain drain and protect the next generation, however, and Grandjean tells us how. First, we need to control all of the 200 industrial chemicals that have already been proven to affect brain functions in adults, as their effects on the developing brain are likely even worse. We must also push for routine testing for brain toxicity, stricter regulation of chemical emissions, and more required disclosure on the part of industries who unleash hazardous chemicals into products and the environment. Decisions can still be made to protect the brains of future generations.
    "In his crisply written, deeply documented book, Dr. Philippe Grandjean, renowned physician and public health specialist, describes the exquisite vulnerability of the developing human brain to toxic chemicals in the environment, a vulnerability that he ascribes to the brain's almost unimaginable complexity. Today, nearly one in every 6 children is born with a neurodevelopmental disorder - a birth defect of the brain. One in 8 has attention deficit disorder. One in 88 is diagnosed with autism spectrum disorder. These rates are far higher than those of a generation ago, and, although they are less publicized, the problems are more prevalent than those caused by thalidomide in the 1960's. The increases are far too rapid to be genetic. They cannot be explained by better diagnosis. How then could they have come to be? Dr. Grandjean has a diagnosis -- the thousands of toxic chemicals that have been released to the environment in the past 40 years with no testing for toxicity. David P. Rall, former Director of the US National Institute of Environmental Health Sciences, once stated that 'If thalidomide had caused a ten-point loss of IQ rather than obvious birth defects of the limbs, it would probably still be on the market'. This is the core message of Dr. Grandjean's 'must read' book." - Philip J. Landrigan, Dean for Global Health, Ethel H. Wise Professor and Chairman and Director, Children's Environmental Health Center, Mount Sinai School of Medicine

  • This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children's environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects.

    Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children's health can be affected by harmful chemicals and other environmental toxicants.

  • Cet ouvrage est une réédition numérique d'un livre paru au XXe siècle, désormais indisponible dans son format d'origine.

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