Most research in the life sciences involves a core set of molecular-based equipment and methods, for which there is no shortage of step-by-step protocols. Nonetheless, there remains an exceedingly high number of inquiries placed to commercial technical support groups, especially regarding problems. Molecular Biology Problem Solver: A Laboratory Guide asks the reader to consider crucial questions, such as: Have you selected the most appropriate research strategy? Have you identified the issues critical to your successful application of a technique? Are you familiar with the limitations of a given technique? When should common procedural rules of thumb not be applied? What strategies could you apply to resolve a problem? A unique question-based format reviews common assumptions and laboratory practices, with the aim of offering a firm understanding of how techniques and procedures work, as well as how to avoid problems. Some major issues explored by the book's expert contributors include: Working safely with biological samples and radioactive materials DNA and RNA purification PCR Protein and nucleid acid hybridization Prokaryotic and eukaryotic expression systems Properly using and maintaining laboratory equipment
Flow cytometry continually amazes scientists with its ever-expanding utility. Advances in flow cytometry have opened new directions in theoretical science, clinical diagnosis, and medical practice. The new edition of Flow Cytometry: First Principles provides a thorough update of this now classic text, reflecting innovations in the field while outlining the fundamental elements of instrumentation, sample preparation, and data analysis.Flow Cytometry: First Principles, Second Edition explains the basic principles of flow cytometry, surveying its primary scientific and clinical applications and highlighting state-of-the-art techniques at the frontiers of research. This edition contains extensive revisions of all chapters, including new discussions on fluorochrome and laser options for multicolor analysis, an additionalsection on apoptosis in the chapter on DNA, and new chapters onintracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology. This essential resource:Assumes no prior knowledge of flow cytometryProgresses with an informal, engaging lecture style from simpleto more complex conceptsOffers a clear introduction to new vocabulary, principles of instrumentation, and strategies for data analysisEmphasizes the theory relevant to all flow cytometry, with examples from a variety of clinical and scientific fieldsFlow Cytometry: First Principles, Second Edition provides scientists, clinicians, technologists, and students with the knowledge necessary for beginning the practice of flow cytometry and for understanding related literature.
"I would strongly recommend it for library purchase and the reading list of advanced students in this field." Microbiology Today, May 2009 Nearly a decade since its landmark publication, this book has been thoroughly revised in this valuable new editionLike the successful first edition, Microbial Ecology of the Oceans, Second Edition is unique and fills a void in the rapidly growing fields of marine microbiology, microbial ecology, and microbial oceanography. Here, a carefully selected team of international experts explores issues of enduring importance to microbial ecologists, including:Genomes and metagenomes of marine microbesMicrobial evolution, as revealed by molecular techniquesMicrobes in carbon budgets and cyclesViruses and grazers of bacteriaMicrobes and N cycle reactions in sedimentsThe role of microbes in food web dynamicsBiogeochemical cycles in the oceanIn addition to drawing on the long history of microbiology, the contributors also include discussions of the latest advances in biological and chemical oceanography to examine the role of microbes and viruses in the oceans.Richly illustrated with black-and-white photographs and drawings, and complemented with a comprehensive list of additional reading for each chapter, this important new edition provides readers with current information in the fields of marine microbiology and microbial ecology. It is designed for students and researchers in biological and chemical oceanography, geochemistry, marine chemistry, freshwater ecology, and general microbiology. It is also appropriate for professionals and advanced students in related fields.
A unique resource on sleep medicine Written by contemporary experts from around the world, Sleep: A Comprehensive Handbook covers the entire field of sleep medicine. Taking a novel approach, the text features both syndrome- and patient-oriented coverage, making it ideally suited for both clinical use and academic study. Sleep: A Comprehensive Handbook begins with a brief introduction to the basic science of sleep, from neurobiology to physiologic processes. This leads into sections offering comprehensive coverage of insomnia, sleep apnea, narcolepsy, parasomnias, movement disorders, and much more. Sleep and related disorders are also discussed, followed by chapters on considerations for special patient groups. Special materials for practitioners include a sample interview and questionnaire as well as a chapter on operating and managing a sleep center. The text concludes with discussions of sleep assessment methods such as polysomnography, actigraphy, and video EEG monitoring. With full coverage of over 100 key topics in sleep medicine, Sleep: A Comprehensive Handbook offers the most practical, thorough, yet handy resource available on adult and pediatric sleep medicine. Praise from the reviews: "...no other publication in the field can begin to compare with the breadth or depth of the 'Handbook'...I cannot imagine a functioning sleep disorders clinic without at least one copy on standby as a ready reference." PscyCRITIQUES "Sleep: A Comprehensive Handbook is a first-rate textbook with concise, up-to-date information covering a wide range of subjects pertinent to the practice of sleep medicine." DOODY'S HEALTH SERVICES
An Introduction to Molecular Medicine and Gene Therapy
Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy:
* Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations
* Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases
* Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter
* Contains appendices on commercial implications and a review of the history of gene therapy
This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
This multimedia resource offers a complete introduction to neuroanatomy with superb, clear and thoroughly labeled images and illustrations within an elegant navigation structure. It emphasizes the practical aspects of how to identify neuroanatomical structures, with quizzes and chapter self-assessments. The content is organised into sections covering light-microscopic neurohistology, electron-microscopic neurohistology, skull-meninges-spinal cord, gross anatomy of the brain, sectional anatomy of the brain, and brain imaging. Digital Neuroanatomy: An Interactive CD Atlas with Review Text features: Richly illustrated throughout with over 300 images A brief printed textbook that follows the same organization and approach, reviewing all the main concepts Self-grading quizzes with answers that include a detailed explanation A help mode offering animated explanations of the primary programme features A dynamic navigation structure providing direct access to specific points in the large volume of content An ideal tool for teaching, self-instruction, and self-assessment, Digital Neuroanatomy: An Interactive CD Atlas with Review Text is an invaluable resource for students, teachers, and scientists alike. It is useful for undergraduate courses and graduate courses in medical, anatomy, radiology, dental, and pharmacy schools, as well as those in schools of dentistry and physical therapy.
A complete examination of the uses of the atomic force microscope in biology and medicine
This cutting-edge text, written by a team of leading experts, is the first detailed examination of the latest, most powerful scanning probe microscope, the atomic force microscope (AFM). Using the AFM, in combination with conventional tools and techniques, readers gain a profound understanding of the cell, subcellular organelles, and biomolecular structure and function.
The text begins with three chapters describing the molecular machinery and mechanism of cell secretion and membrane fusion in cells, using approaches that combine AFM, electron microscopy, X-ray diffraction, photon correlation spectroscopy, molecular biology, biochemistry, and electrophysiology. The discovery of a new cellular structure the "porosome" or fusion pore--the cells secretory machinery, the molecular mechanism of membrane fusion in cells, and the expulsion of intravesicular contents during cell secretion are outlined in the first three chapters. The book also covers:
* Identification of the "porosome" in the growth hormone secreting cell of the pituitary gland
* Probing the structural and physical properties of microbial cell surfaces
* Scanning probe microscopic characterization of the higher plant cell wall and its components
* Case studies of nano drug delivery systems using engineered dendrimers
* AFM techniques for studying living cells
* Investigating the intermolecular forces of leukocyte adhesion molecules
* Protein-protein interactions
* Micromechanical properties of lipid bilayers and vesicles
The text concludes with four chapters that examine new and emerging approaches in the use of force microscopy in biology and medicine.
This text is ideal for advanced undergraduate and graduate students and researchers in cell and molecular biology, genetics, genomics, physiology, neuroscience, biophysics, and biochemistry. Not only does it provide the theory, but also practical considerations such as the selection of the right tools and approach.
An essential foundation for the practice of forensic anthropology This text is the first of its level written in more than twenty years. It serves as a summary and guide to the core material that needs to be mastered and evaluated for the practice of forensic anthropology. The text is divided into three parts that collectively provide a solid base in theory and methodology: Part One, "Background Setting for Forensic Anthropology," introduces the field and discusses the role of forensic anthropology in historic context. Part Two, "Towards Personal Identification," discusses initial assessments of skeletal remains; determining sex, age, ancestral background, and stature; and skeletal markers of activity and life history. Part Three, "Principal Anthropological Roles in Medical-Legal Investigation," examines trauma; the postmortem period; professionalism, ethics, and the expert witness; and genetics and DNA. The critical and evaluative approach to the primary literature stresses the inherent biological constraints on degrees of precision and certainty, and cautions about potential pitfalls. The practical focus, coupled with theoretical basics, make Fundamentals of Forensic Anthropology ideal for upper-level undergraduates and graduate students in biological anthropology as well as forensic scientists in allied fields of medical-legal investigation.
A complete review of the issues with specific recommendations and guidelines.
With over 1,000 tests commercially available, genetic testing is revolutionizing medicine. Health care professionals diagnosing and treating patients today must consider genetic factors, the risks and limitations of genetic testing, and the relevant law. Genetic Testing: Care, Consent, and Liability offers the only complete, practical treatment of the genetic, clinical, ethical, and legal issue surrounding genetic testing. The authors present protocols, policies, and models of care that are currently in use, and explain the legal framework for genetic testing and counseling that has developed in North America, particularly with regard to the law of medical malpractice.
This essential book features an international roster of esteemed contributors including, Nancy P. Callanan, Bonnie S. LeRoy, Carole H. Browner, H. Mabel Preloran, Riyana Babul-Hirji, Cheryl Shuman, M.J. Esplen, Maren T. Scheuner, Dena S. Davis, JonBeckwith, Lisa Geller, Mark A. Hall, Andrew R. MacRae, David Chitayat, Roxanne Mykitiuk, Stephanie Turnham, Mireille Lacroix, Jinger G, Hoop, Edwin H, Cook, Jr., S. H. Dinwiddie, Elliot S. Gershon, C. Anthony Rupar, Lynn Holt, Bruce R. Korf, Anne Summers, S. Annie Adams, Daniel L. Van Dyke, Rhett P. Ketterling, Erik C. Thorland, Timothy Caulfield, Lorraine Sheremeta, Richard Gold, Jon F. Merz, David Castle, Peter J. Bridge, JS Parboosingh, Patricia T. Kelly, Julianne M. O'Daniel, Allyn McConkie-Rosell, Beatrice Godard, Bartha Maria Knoppers, David Weisbrot.
The coverage also includes:
* Genetic screening, including prenatal, neonatal, carrier, and susceptibility testing
* Diagnosis, risk assessment, confidentiality, and clinical/legal issues related to follow-up
* Interpreting test results and communicating them to patients
* psychological considerations
* Informed consent
* Family history evaluations
* Referral to medical geneticists and genetic counselors
Genetic Testing Care, Consent, and Liability is a must-have resource for clinical geneticists, genetic counselors, specialists, family physicians, nurses, public health professionals, and medical students.
This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly written chapters offer reviews of state of the art topics such as molecular classification, early detection, SNPs in cancer, data mining, tissue microarrays, protein and antibody arrays, and drug targets.
A step-by-step guide to using computational tools to solve problems in cell biology
Combining expert discussion with examples that can be reproduced by the reader, this text introduces an array of informatics tools that are available for analyzing biological data and modeling cellular processes. You learn to fully leverage public databases and create your own computational models. All that you need is a working knowledge of algebra and cellular biology; the author provides all the other tools you need to understand the necessary statistical and mathematical methods.
Coverage is divided into two main categories:
Molecular sequence database chapters are dedicated to gaining an understanding of tools and strategies-including queries, alignment methods, and statistical significance measures-needed to improve searches for sequence similarity, protein families, and putative functional domains. Discussions of sequence alignments and biological database searching focus on publicly available resources used for background research and the characterization of novel gene products.
Modeling chapters take you through all the steps involved in creating a computational model for such basic research areas as cell cycle, calcium dynamics, and glycolysis. Each chapter introduces a new simulation tooland is based on published research. The combination creates a rich context for ongoing skill and knowledge development in modeling biological research systems.
Students and professional cell biologists can develop the basic skills needed to learn computational cell biology. This text, with its step-by-step instruction, enables you to test and develop your new bioinformatics and modeling skills. References are provided to help you take advantage of more advanced techniques, technologies, and training.
Tailoring retirement for successful business leaders Traditional retirement planning fails to meet the needs of wealthy baby boomers, particularly those who are business leaders. There is no "one size fits all" answer. Wealth Regeneration at Retirement: Planning for a Lifetime of Leadership presents an alternative - one that acts more like a GPS. The authors, Kaycee Krysty and Bob Moser, leaders of the highly regarded Seattle-based wealth management firm, Laird Norton Tyee, use a proprietary discipline, Wealth Regeneration®, to calculate the route to retirement and beyond for those at the top. The authors challenge successful boomers to redefine retirement on their own terms. They outline a process to create a sustainable plan to achieve retirement objectives. Their years of experience in counseling CEO's and business founders through transitions is reflected throughout. For many successful boomers, the answer to the prospect of retirement has been, "I'd rather not." Yet change is inevitable. Wealth Regeneration at Retirement provides a thoughtful and thorough way for leaders to move onward. Describing Wealth Regeneration in a digestible, actionable format, the book provides the framework, tools, and techniques that successful baby boomers and their advisors need to incorporate this innovative approach for a lifetime of leadership and legacy. Packed with learning aids, including graphics, diagrams, worksheets and exercises, the book helps readers build a unique life plan that is about more than simply retirement. The book includes: A proprietary approach to retirement planning that changes seamlessly when times and circumstances change A four component methodology - Where You Are; What You Want; What to Do; and Make it Happen - to ensure continuous feedback, accountability, and measurement of lifetime goals Retirement planning expertise from wealth management firm Laird Norton Tyee Wealth Regeneration at Retirement: Planning for a Lifetime of Leadership is artfully illustrated and filled with practical advice for wealthy baby boomers and the financial advisors they rely on. It explains exactly how to build a personalized and sustainable plan for retirement no matter where life may lead.
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what's wrong with my mouse? Turn to What's Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.
This comprehensive publication covers all aspects of image formation in modern medical imaging modalities, from radiography, fluoroscopy, and computed tomography, to magnetic resonance imaging and ultrasound. It addresses the techniques and instrumentation used in the rapidly changing field of medical imaging. Now in its fourth edition, this text provides the reader with the tools necessary to be comfortable with the physical principles, equipment, and procedures used in diagnostic imaging, as well as appreciate the capabilities and limitations of the technologies.
Eric Engel and Stylianos Antonarakis have written the most authoritative and vital reference on molecular and clinical aspects of uniparental disomy (UPD) and genomic imprinting to date. Genomic Imprinting and Uniparental Disomy in Medicine features comprehensive overviews of a multitude of genetic disorders linked to UPD, with a strong emphasis on clinical consequences. This book will provide readers with the tools necessary to identify and treat diseases associated with nontraditional chromosomal inheritance.
Genomic Imprinting and Uniparental Disomy in Medicine features handy tables summarizing clinical phenotypes and chromosomal involvement in UPD, as well as clear illustrations on imprinting mechanisms and diagnostic testing. This authoritative, completely up-to-date practical reference will be useful for any clinical geneticist, genetic counselor, physician, or researcher encountering patients with such disorders or studying complex disease mechanisms.
Cellular Aspects of HIV Infection provides a highly readable, detailed overview of the state of the art in modern HIV research at the cellular level. This volume brings together renowned experts who have provided concise, synthetic treatments of the biology of HIV infection. It presents these descriptions and analyses with particular attention to the techniques of flow cytometry that have allowed us to not only observe the course of HIV infection and the immune system's response to it, but have also increased our ability to treat patients and understand their response to therapy.
The book is divided into five sections covering molecules and cells, pathophysiological processes, technologies, and organisms. A perspective on future therapies concludes the book. Each chapter offers an intelligent, concise synthesis of the topic, highlighting the biological principles and technologies involved in the study of HIV infection. Cellular Aspects of HIV Infection is an indispensable, up-to-date guide for immunologists, virologists, clinicians, and researchers.
"...a wonderful compendium of current in vitro approaches that will be a useful resource to those just starting to work with an epithelial cell system as well as those that have been working with them for years and years."
This completely revised and expanded new edition provides detailed descriptions of fundamental and practical aspects relating to the in vitro cultivation of disparate types of epithelia. In recent years, the use of epithelial cell culture in cell biology and tissue engineering has increased dramatically. This revision reflects those advances by including new chapters on the culture of animal and human hepatocytes, kidney epithelium, and bladder epithelium. Each chapter provides an introductory review of the principles and advantages of the particular method, followed by detailed protocols, practical tips, alternate methods, and a useful list of materials and suppliers.
The Second Edition of Connective Tissue and Its Heritable Disorders: Molecular, Genetic, and Medical Aspects is the definitive reference text in its field, with over 40% more pages on the nature, diagnosis, and treatment of disease than its predecessor. Collecting new research on disorders detailed in the first edition as well as on those previously excluded, editors Peter Royce and Beat Steinmann provide the most up-to-date clinical and scientific information for medical specialists treating affected individuals. Features of this revised and updated volume include detailed reviews of the clinical diagnosis, mode of inheritance, risk of recurrence, and prenatal diagnosis of each inherited connective tissue disorder; a thorough description of the morphology of connective tissues; a completely updated and revised section on the biology of the extracellular matrix; and the addition of syndromes such as craniosyntosis, and disorders of sulfate metabolism.
"There is a palpable need for business to explore the issues Dhanda raises. Guiding Icarus offers a flight plan."
-from the Foreword by Philip R. Reilly
Merging Bioethics with Corporate Interests
Rahul K. Dhanda
While bioethicists may enjoy the most thorough appreciation of both the promise and perils of new biotechnologies, international corporations are in fact the entities generating these technologies and determining their application. An industry insider versed in the language of bioethics, Rahul Dhanda offers in Guiding Icarus: Merging Bioethics with Corporate Interests a Rosetta stone to these two camps, explaining why each needs the other, why their disparate concerns often cohere, and why an ethical business is likely a successful one.
The author develops a dialogue between bioethics and corporate interests by examining case studies of several hot-button issues, including:
* Genetically modified foods
* DNA data banking
* Personalized medicine
* Stem cell research
In each instance he provides a treatment of the particular science under consideration, a list of the benefits of the technology, a description of the ethical issues involved, an account of past industry response, and recommendations for future action. Given the expansive nature of biotechnology, ramifications in the pharmaceutical and agricultural industries are covered in depth as well. The book also features a Foreword by world-renowned bioethicist and biotechnology CEO Philip R. Reilly as well as a step-by-step discussion of the components of business and bioethical issues.
Written for a general audience, Guiding Icarus will be particularly useful to biotechnologists, regulatory affairs managers, and corporate officers of biotechnology firms, as well as bioethicists in the academic community. Dhanda's peerless text provides a unique tool for understanding and addressing the ethical dilemmas confronting society in the 21st century.
The new edition of this critically praised text continues to provide the most comprehensive overview of the concepts, methods, and research advances in the field. It has been revised and enhanced to capitalize on the strengths of the first edition while keeping it up-to-date in the field of psychiatry. This comprehensive publication now includes new chapters on child psychiatry, community studies, and perinatal studies.
Over the last decade, advances in science and technology have profoundly changed the face of light microscopy. Research scientists need to learn new skills in order to use a modern research microscope-skills such as how to align microscope optics and perform image processing. Fundamentals of Light Microscopy and Electronic Imaging explores the basics of microscope design and use. The comprehensive material discusses the optical principles involved in diffraction and image formation in the light microscope, the basic modes of light microscopy, the components of modern electronic imaging systems, and the image processing operations necessary to acquire and prepare an image.
Written in a practical, accessible style, Fundamentals of Light Microscopy and Electronic Imaging reviews such topics as:
* Illuminators, filters, and isolation of specific wavelengths
* Phase contrast and differential interference contrast
* Properties of polarized light and polarization microscopy
* Fluorescence and confocal laser scanning microscopy
* Digital CCD microscopy and image processing
Each chapter includes practical demonstrations and exercises along with a discussion of the relevant material. In addition, a thorough glossary assists with complex terminology and an appendix contains lists of materials, procedures for specimen preparation, and answers to questions.
An essential resource for both, experienced and novice microscopists.
The resurgence of interest in high-resolution evaluation of single-cell properties has led to examining where current technology stands at the beginning of a new millennium. Engineers and scientists have produced significant advances in cytometric technologies in just the past few years. Emerging Tools for Single-Cell Analysis: Advances in Optical Measurement Technologies stresses the applications and theories behind some of these advances in cell measurement and cell- sorting technologies.
Rapid assessment of the proper function of cells and molecular processes within cells is essential. To that end, new and varying technologies present important diagnostic and prognostic tools relevant to a variety of diseases. Future developments in miniaturization of electronics, micro- and nanomachines, and biomedical engineering are certain to impact cell biology. New analytical technologies are revolutionizing our ability to functionally characterize, isolate, and manipulate single cells. This timely book offers researchers and design engineers much-needed information as they further develop technologies for cell analysis.
By comparing and contrasting various approaches, the authors explain how those technologies converge toward similar goals: evaluating the properties of cells and sorting cells on those properties using optically-based measurement systems. Emerging Tools for Single-Cell Analysis offers scientists and engineers a vision of the exciting possibilities that exist as new technologies are applied to single-cell analysis,
This text tells the story of cells as the unit of life in a colorful and student-friendly manner, taking an "essentials only" approach. By using the successful model of previously published Short Courses, this text succeeds in conveying the key points without overburdening readers with secondary information. The authors (all active researchers and educators) skillfully present concepts by illustrating them with clear diagrams and examples from current research. Special boxed sections focus on the importance of cell biology in medicine and industry today. This text is a completely revised, reorganized, and enhanced revision of From Genes to Cells.
This revision of the now classic Plant Anatomy offers a completely updated review of the structure, function, and development of meristems, cells, and tissues of the plant body. The text follows a logical structure-based organization. Beginning with a general overview, chapters then cover the protoplast, cell wall, and meristems, through to phloem, periderm, and secretory structures. "There are few more iconic texts in botany than Esau's Plant Anatomy... this 3rd edition is a very worthy successor to previous editions..." ANNALS OF BOTANY, June 2007