• “Weaving the threads of astronomy, physics, chemistry, biology, and philosophy into a seamless narrative tapestry, Sean Carroll enthralls us with what we’ve figured out in the universe and humbles us with what we don’t yet understand. Yet in the end, it’s the meaning of it all that feeds your soul of curiosity.” --Neil deGrasse Tyson, host of Cosmos: A SpaceTime Odyssey *Publishers Weekly #1 Most Anticipated Science Book of Spring 2016* Already internationally acclaimed for his elegant, lucid writing on the most challenging notions in modern physics, Sean Carroll is emerging as one of the greatest humanist thinkers of his generation as he brings his extraordinary intellect to bear not only on Higgs bosons and extra dimensions but now also on our deepest personal questions. Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void? Does human purpose and meaning fit into a scientific worldview? In short chapters filled with intriguing historical anecdotes, personal asides, and rigorous exposition, readers learn the difference between how the world works at the quantum level, the cosmic level, and the human level--and then how each connects to the other. Carroll's presentation of the principles that have guided the scientific revolution from Darwin and Einstein to the origins of life, consciousness, and the universe is dazzlingly unique. Carroll shows how an avalanche of discoveries in the past few hundred years has changed our world and what really matters to us. Our lives are dwarfed like never before by the immensity of space and time, but they are redeemed by our capacity to comprehend it and give it meaning. The Big Picture is an unprecedented scientific worldview, a tour de force that will sit on shelves alongside the works of Stephen Hawking, Carl Sagan, Daniel Dennett, and E. O. Wilson for years to come. From the Hardcover edition.

  • We not only share nearly 99% of our genes with chimps, we also have some 35% in common with daffodils. Throughout much of the animal and even plant kingdoms, almost the same ancient genes code for almost the same proteins. And further, to everyone's astonishment, the genes involved in making the complex eyes of fruitflies are close matches to those involved in making the very different eyes of octopuses and people. So what leads to the nature's 'endless forms most beautiful'? bThe key to this mystery is being unravelled by 'Evo Devo' or the new science of evolutionary development biology. By looking at how a single-celled egg gives rise to a complex, multi-billion celled animal, Evo Devo is illuminating exactly how new species - butterflies and zebras, trilobites and dinosaurs, apes and humans - are made and evolved. The key, it turns out, is all about location and timing... bFor anyone who has ever pondered 'where did I come from', Endless Forms Most Beautiful explores our history, both the journey we have all made from egg to adult, and the long trek from the origin of life to the very recent origin of our species.

  • In 1809, when Darwin was born, much of the world was an unexplored wilderness. Our knowledge of the past was nonexistent, and our picture of our species' history little more than a set of fantastic myths and fairytales. But a new era was dawning. Five decades later, On the Origin of the Species was able to draw on the pioneering work of explorers and naturalists to produce a theory that revolutionized our conception of our world. And the revolution didn't stop with the publication of Darwin's masterwork. 150 years later, his 'dangerous idea' is still headline news, denied by many, capable of enraging and dividing, even as biologists decipher the 3-billion-year history of life as written in our very DNA.
    /> This book tells the stories of the most dramatic adventures and important discoveries in two centuries of natural history - from Alexander von Humboldt's epic journeys in South America to the hi-tech genome-reading projects making headlines today - and how they gave birth to and have nourished the evolution revolution.

  • An award-winning biologist takes us on the dramatic expeditions that unearthed the history of life on our planet. Just 150 years ago, most of our world was an unexplored wilderness. Our sense of its age was vague and vastly off the mark, and much of the knowledge of our own species history was a set of fantastic myths and fairy tales. In the tradition of The Microbe Hunters and Gods, Graves, and Scholars, Sean Carroll leads a rousing voyage that recounts the most important discoveries in two centuries of natural history: from Darwins trip around the world to Charles Walcotts discovery of pre-Cambrian life in the Grand Canyon; from Louis and Mary Leakeys investigation of our deepest past in East Africa to the trailblazers in modern laboratories who have located a time clock in our DNA.

  • With two new lead authors, the sixth edition of Psychiatric Diagnosis continues its thirty-five year tradition of providing a clear, critical and well-documented overview of major psychiatric syndromes, with minimum inclusion of unwieldy theories or clinical opinions. Medical students and psychiatric residents will continue to find this new edition to be a unique guide to the field-a volume that concisely yet comprehensively dissects major psychiatric disorders. Well-known for providing a thorough yet concise view of the natural history of basic psychiatric disorders, this popular text has been extensively updated, chapter by chapter, in this sixth edition. Terminology has been made consistent with DSM-IV-TR and updates made to include recent genetic and neurobiological findings. In the classification of psychiatric disorders, new data on follow-up and family/genetic studies, confirming and extending previous research, are provided. As in previous editions, each chapter systematically covers the definition, historical background, epidemiology, clinical picture, natural history, complications, family studies, differential diagnosis, and clinical management of each disorder.
    Some specific areas of new material include the long term course of mood disorders, genetics and neuro-imaging of schizophrenia and mood and other disorders, cognitive changes in relation to depression and dementia, brain stimulation techniques, outcome studies of eating disorders, and epidemiology of drug use disorders. In accordance with current medical community interest and research, entirely new chapters on posttraumatic stress disorder and borderline personality disorder have been included. Additionally, a new introduction reviews the background of medical model psychiatry and the empirical approach to psychiatric nosology. With this new edition, medical students and psychiatric residents will continue to discover that no other text provides such a lucid, well-documented and critically sound overview of the major syndromes in psychiatry.

  • In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development.
    An accessible text, focusing on the most well-known genes, developmental processes and taxa.
    Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels.
    Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species.
    Provides in-depth focus on key concepts through well-developed case studies.
    Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary.
    Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology.An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at HigherEducation@wiley.com for more information.

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